Introduction: High quality of work life is known as basic prerequisite of empowering human resources in healthcare system. Nurses’ productivity plays an important role in organizations’ success. Knowing the correlation between quality of work life and productivity, managers can improve staffs’ productivity by promoting nurses’ quality of work life. This study aimed at assessing relationships between quality of work life and productivity of nurses.

Methods: This cross-sectional correlation study was conducted with a random sample of 360 nurses drawn from hospitals affiliated to Tehran University of Medical Sciences. Data were gathered through self-administered questionnaires containing work quality of life questionnaire (45 questions on a likert rating scale) and productivity questionnaire (25 questions on a likert rating scale). Both questionnaires were developed by the researchers. All statistics were computed using the SPSS software (version 13) with pearson and K square tests.

Results: Findings revealed that 31.9% of the nurses considered their productivity level, moderate. 41.9% of them reported their work quality of life at moderate level. Only 10% of them believed that their work quality of life is good. The results demonstrated statistically significant correlation between work quality of life and productivity level of nurses (r=0.357, P<0.001).

Conclusion: Since just 0.1 of nurses reported their productivity and quality of work life good, managers should apply the appropriate strategies to promote nurses’ quality of work life and provide the ground for improving the quality of care and productivity of nurses.