Introduction: Cardiovascular diseases and their related complications, disability and mortality are proliferating in Iran. Developing and applying native models can be an important strategy to control such complications, more effectively. Organizational Culture Improvement Model of patient education was developed through a native qualitative research study which was tested in this study. The study aimed at investigating the effect of Organizational Culture Improvement Model of patient education on anxiety and satisfaction of patient with coronary artery disease.

Method: Using quasi- experimental method, 70 patients with coronary artery diseases purposely and five nurses through randomized sampling were selected. Data were collected using “The Eshpel Burgers’ anxiety questionnaire” and “patients’ satisfaction questionnaire”.

 Results: Findings demonstrated significant statistically reduced level of anxiety [before 58.81 and after 30.15 in intervention group and / before 58.74 and after 54.36 in control group] and increased patients’ satisfaction [before 23.86 and after 52.57 in intervention group and / before 24.88 and after 26.7 in control group] in intervention group, compared to control group, after the intervention.

 Conclusion: Organizational Culture Improvement Model of patient education can have impacts on anxiety and satisfaction in patient with coronary artery disease.