Nutritional support is one of the main pillars of care in patients under mechanical ventilation due to acute conditions and low level of consciousness. The purpose of this study was to compare the effect of two methods of enteral feeding, bolus and continuous, on laboratory indicators and the incidence of diarrhea in patients under mechanical ventilation. method: It was a randomized clinical trial study. The research population was made up of all intubated patients under mechanical ventilation of Imam Khomeini Hospital, Tehran University of Medical Sciences, and 34 patients from the special care department were randomly assigned to two intervention and control groups based on their case number. Consent was obtained from patients' companions to participate in the study. The intervention group was fed by continuous feeding method and the control group was fed by routine method (Bolus) for one week. Laboratory indicators (albumin and lactate) were measured at the beginning of the intervention and also one week after the intervention, glucose every 6 hours and frequency of diarrhea were measured and in the basic information registration sheet, the laboratory index registration and the frequency of defecation sheet, were recorded. Tables of descriptive statistics and results of statistical tests and SPSS software version 20 were used to describe the data. Results: There was no significant difference between the changes in albumin and lactate levels in the two groups before and after the intervention (P<0.05). Although the amount of lactate in both groups decreased significantly after the intervention compared to before. Also, except for the first day, there was no significant difference between the two groups in any of the intervention days (P<0.05). There was no significant difference in the frequency of diarrhea between the two groups during one week (P<0.05). Conclusion: Considering the lack of significant differences between the effects of these two nutritional methods on laboratory indicators, the use of a method that is safer and more affordable can be the priority of the nutritional method of these patients; Although it is recommended to start feeding as soon as possible in these patients to reduce the lactate level.
rooddehghan Z, seyyedi J, mohammadi M, haghani S, karimi R. A comparative study of the effect of two methods of enteral feeding, bolus and continuous, on laboratory indicators and the incidence of diarrhea in patients under mechanical ventilation.. IJNR 2024; 19 (3) :88-99 URL: http://ijnr.ir/article-1-2796-en.html