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IJNR 2018, 13(1): 40-46 Back to browse issues page
Effects of two Exercise Modalities of Sprint Interval Training and Combined Training (Strength-Aerobic) on Serum Apelin levels and Insulin Resistance in Women with Type 2 Diabetes
Samira Nasiri , Ebrahim Banitalebi * , Mohammad Faramarzi
Department of Sport Sciences, Shahrekord University, Shahrekord, Iran , banitalebi.e@gmail.com
Abstract:   (2052 Views)
Introduction: Exercise activity is an effective treatment tool for the management of type 2 diabetic patients. The purpose of this study is to investigate the effects of eight weeks combined and sprint interval training (SIT) on serum apelin levels and insulin resistance in women with type 2 diabetes.
Methods: Fifty-two overweight female type 2 diabetic patients (aged 45-60 years old, BMI > 30) with HbA1C value of 6.5% or were assessed for eligibility. Participants were assigned to SIT group (n = 17), combined training group (n = 17), and control group (n = 18) according to HbA1c levels. The exercises included 12 weeks of combined training and SIT. To determine the differences between groups, a statistical analysis of covariance and a meaningful LSD test were used to determine the difference between groups.
Results: Difference was significant for the fasting blood glucose in the SIT groups (p<0.001). Serum insulin levels showed significant increases in the SIT (p<0.001) and Com (p=0.001). Changes in apelin were not significantly different within SIT and combined training groups (p = 0.13 and p = 0.09, respectively). The data showed significant differences in insulin resistance index (HOMA-IR) in SIT (p<0.001) and Com (p=0.008). Furthermore, the ANCOVA test showed that there were no significant differences in fasting blood glucose concentrations (F = 1.853, p = 0.171), apelin (F = 0.511, p = 0.12) But, significant differences were seen between groups in insulin (F = 3.622, p = 0.036), and HOMA-IR (F = 5.511, p = 0.008).
Conclusion: exercise training independent of mode of training is an effective training method to improve glycemic control in woman with type 2 diabetes.
Keywords: SIT and Combined Training, Apelin, Type 2 Diabetes.
Full-Text [PDF 472 kb]   (337 Downloads)    
Type of Study: Rehabilitation Nursing | Subject: rehabilitation
Received: 2016/10/1 | Accepted: 2018/04/8 | Published: 2018/04/8
1. Simpson SH, Corabian P, Jacobs P, Johnson JA. The cost of major comorbidity in people with diabetes mellitus. CMAJ. 2003;168(13):1661-7. [PMID] [PMCID]
2. Samadian Z, Tofighian A, Mehdizade A. [The effect of 12 weeks of combined training on serum resistin levels and glycemic index in obese postmenopausal women with type 2 diabetes]. Diabetes Metab J. 2013;12(6):524-33.
3. Lambers S, Van Laethem C, Van Acker K, Calders P. Influence of combined exercise training on indices of obesity, diabetes and cardiovascular risk in type 2 diabetes patients. Clin Rehabil. 2008;22(6):483-92. [DOI:10.1177/0269215508084582] [PMID]
4. Mann S, Beedie C, Jimenez A. Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Med. 2014;44(2):211-21. [DOI:10.1007/s40279-013-0110-5] [PMID] [PMCID]
5. Habibi N, Marandi M. [The effect of 12 weeks of yoga on serum levels of glucose,insulin and triglyceride woman with type 2 diabetes]. Diabetes Metab J. 2013. [DOI:10.1016/S1262-3636(13)71928-1]
6. Zamanpour L, Banitalebi E, Amirhosseini SE. The effect of sprint training and combined aerobic and strength training on some inflammatory markers and insulin resistance in women with diabetes mellitus (T2dm). Iranian J Diabetes Metab. 2016;15(5):300-11.
7. Soriguer F, Garrido-Sanchez L, Garcia-Serrano S, Garcia-Almeida JM, Garcia-Arnes J, Tinahones FJ, et al. Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus. Obes Surg. 2009;19(11):1574-80. [DOI:10.1007/s11695-009-9955-y] [PMID]
8. Besse-Patin A, Montastier E, Vinel C, Castan-Laurell I, Louche K, Dray C, et al. Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine. Int J Obes (Lond). 2014;38(5):707-13. [DOI:10.1038/ijo.2013.158] [PMID]
9. Kadoglou NP, Vrabas IS, Kapelouzou A, Lampropoulos S, Sailer N, Kostakis A, et al. The impact of aerobic exercise training on novel adipokines, apelin and ghrelin, in patients with type 2 diabetes. Med Sci Monit. 2012;18(5):CR290-5. [DOI:10.12659/MSM.882734] [PMID] [PMCID]
10. Revdal A. Low-volume interval training improves cardiovascular risk factors in type 2 diabetes: A randomized controlled trial: Norges teknisk-naturvitenskapelige universitet, Det medisinske fakultet, Institutt for sirkulasjon og bildediagnostikk; 2014.
11. Mannarino M, Tonelli M, Allan GM. Tools for practice: screening and diagnosis of type 2 diabetes with HbA1c. Can Fam Physician. 2013;59(1):42. [PMID] [PMCID]
12. Larose J, Sigal RJ, Khandwala F, Kenny GP. Comparison of strength development with resistance training and combined exercise training in type 2 diabetes. Scand J Med Sci Sports. 2012;22(4):e45-54. [DOI:10.1111/j.1600-0838.2011.01412.x] [PMID]
13. Davis JN, Tung A, Chak SS, Ventura EE, Byrd-Williams CE, Alexander KE, et al. Aerobic and strength training reduces adiposity in overweight Latina adolescents. Med Sci Sports Exerc. 2009;41(7):1494-503. [DOI:10.1249/MSS.0b013e31819b6aea] [PMID] [PMCID]
14. Karavirta L, Hakkinen K, Kauhanen A, Arija-Blazquez A, Sillanpaa E, Rinkinen N, et al. Individual responses to combined endurance and strength training in older adults. Med Sci Sports Exerc. 2011;43(3):484-90. [DOI:10.1249/MSS.0b013e3181f1bf0d] [PMID]
15. Gibala MJ, Little JP, van Essen M, Wilkin GP, Burgomaster KA, Safdar A, et al. Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance. J Physiol. 2006;575(Pt 3):901-11. [DOI:10.1113/jphysiol.2006.112094] [PMID] [PMCID]
16. Hovanloo F, Arefirad T, Ahmadizad S. Effects of sprint interval and continuous endurance training on serum levels of inflammatory biomarkers. J Diabetes Metab Disord. 2013;12(1):22. [DOI:10.1186/2251-6581-12-22] [PMID] [PMCID]
17. Roubenoff R, Hughes VA. Sarcopenia: current concepts. J Gerontol A Biol Sci Med Sci. 2000;55(12):M716-24. [DOI:10.1093/gerona/55.12.M716] [PMID]
18. Higuchi K, Masaki T, Gotoh K, Chiba S, Katsuragi I, Tanaka K, et al. Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice. Endocrinology. 2007;148(6):2690-7. [DOI:10.1210/en.2006-1270] [PMID]
19. Sheibani S, Hanachi P, Refahiat MA. Effect of Aerobic Exercise on Serum Concentration of Apelin, TNFalpha and Insulin in Obese Women. Iran J Basic Med Sci. 2012;15(6):1196-201. [PMID] [PMCID]
20. Choi K, Kim YB. Molecular mechanism of insulin resistance in obesity and type 2 diabetes. Korean J Intern Med. 2010;25(2):119-29. [DOI:10.3904/kjim.2010.25.2.119] [PMID] [PMCID]
21. Colberg SR, Sigal RJ, Fernhall B, Regensteiner JG, Blissmer BJ, Rubin RR, et al. Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care. 2010;33(12):e147-67. https://doi.org/10.2337/dc10-1548 [DOI:10.2337/dc10-9990]
22. Perri MG, Anton SD, Durning PE, Ketterson TU, Sydeman SJ, Berlant NE, et al. Adherence to exercise prescriptions: effects of prescribing moderate versus higher levels of intensity and frequency. Health Psychol. 2002;21(5):452-8. [DOI:10.1037/0278-6133.21.5.452] [PMID]
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Nasiri S, Banitalebi E, Faramarzi M. Effects of two Exercise Modalities of Sprint Interval Training and Combined Training (Strength-Aerobic) on Serum Apelin levels and Insulin Resistance in Women with Type 2 Diabetes. IJNR. 2018; 13 (1) :40-46
URL: http://ijnr.ir/article-1-1812-en.html

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